Virginia Commonwealth Univeristy

Practicing Excellence in Transfusion Therapy

Clinical reviews

Blood transfusion lab

  1. Brophy GM, Sheehan V, Shapiro MJ, et al. A US multicenter, retrospective, observational study of erythropoiesis-stimulating agent utilization in anemic, critically ill patients admitted to the intensive care unit. Clin Ther. 2008;30(12):2324-2334. doi: 10.1016/j.clinthera.2008.12.024; 10.1016/j.clinthera.2008.12.024.
  2. 2. Dech ZF, Szaflarski NL. Nursing strategies to minimize blood loss associated with phlebotomy. AACN Clin Issues. 1996;7(2):277-287.
  3. 3. Garfinkle M, Lawler PR, Filion KB, Eisenberg MJ. Red blood cell transfusion and mortality among patients hospitalized for acute coronary syndromes: A systematic review. Int J Cardiol. 2013;164(2):151-157. doi: 10.1016/j.ijcard.2011.12.118; 10.1016/j.ijcard.2011.12.118.
  4. 4. Jassar AS, Ford PA, Haber HL, et al. Cardiac surgery in jehovah's witness patients: Ten-year experience. Ann Thorac Surg. 2012;93(1):19-25. doi: 10.1016/j.athoracsur.2011.06.029; 10.1016/j.athoracsur.2011.06.029.
  5. 5. Lawler PR, Filion KB, Dourian T, Atallah R, Garfinkle M, Eisenberg MJ. Anemia and mortality in acute coronary syndromes: A systematic review and meta-analysis. Am Heart J. 2013;165(2):143-53.e5. doi: 10.1016/j.ahj.2012.10.024; 10.1016/j.ahj.2012.10.024.
  6. 6. Lyon AW, Chin AC, Slotsve GA, Lyon ME. Simulation of repetitive diagnostic blood loss and onset of iatrogenic anemia in critical care patients with a mathematical model. Comput Biol Med. 2013;43(2):84-90. doi: 10.1016/j.compbiomed.2012.11.008; 10.1016/j.compbiomed.2012.11.008.
  7. 7. Murphy EL, Kwaan N, Looney MR, et al. Risk factors and outcomes in transfusion-associated circulatory overload. Am J Med. 2013;126(4):357.e29-357.e38. doi: 10.1016/j.amjmed.2012.08.019; 10.1016/j.amjmed.2012.08.019.
  8. 8. Retter A, Wyncoll D, Pearse R, et al. Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients. Br J Haematol. 2013;160(4):445-464. doi: 10.1111/bjh.12143; 10.1111/bjh.12143.
  9. 9. Sayah DM, Looney MR, Toy P. Transfusion reactions: Newer concepts on the pathophysiology, incidence, treatment, and prevention of transfusion-related acute lung injury. Crit Care Clin. 2012;28(3):363-72, v. doi: 10.1016/j.ccc.2012.04.001; 10.1016/j.ccc.2012.04.001.
  10. 10. Shander A, Hofmann A, Ozawa S, Theusinger OM, Gombotz H, Spahn DR. Activity-based costs of blood transfusions in surgical patients at four hospitals. Transfusion. 2010;50(4):753-765. doi: 10.1111/j.1537-2995.2009.02518.x; 10.1111/j.1537-2995.2009.02518.x.
  11. 11. Shander A, Javidroozi M, Ozawa S, Hare GM. What is really dangerous: Anaemia or transfusion? Br J Anaesth. 2011;107 Suppl 1:i41-59. doi: 10.1093/bja/aer350; 10.1093/bja/aer350.
  12. 12. Society of Thoracic Surgeons Blood Conservation Guideline Task Force, Ferraris VA, Ferraris SP, et al. Perioperative blood transfusion and blood conservation in cardiac surgery: The society of thoracic surgeons and the society of cardiovascular anesthesiologists clinical practice guideline. Ann Thorac Surg. 2007;83(5 Suppl):S27-86. doi: 10.1016/j.athoracsur.2007.02.099.
  13. 13. Thavendiranathan P, Bagai A, Ebidia A, Detsky AS, Choudhry NK. Do blood tests cause anemia in hospitalized patients? the effect of diagnostic phlebotomy on hemoglobin and hematocrit levels. J Gen Intern Med. 2005;20(6):520-524. doi: 10.1111/j.1525-1497.2005.0094.x.
  14. Thomas J, Jensen L, Nahirniak S, Gibney RT. Anemia and blood transfusion practices in the critically ill: A prospective cohort review. Heart Lung. 2010;39(3):217-225. doi: 10.1016/j.hrtlng.2009.07.002; 10.1016/j.hrtlng.2009.07.002.
  15. von Haehling S, Schefold JC, Hodoscek LM, et al. Anaemia is an independent predictor of death in patients hospitalized for acute heart failure. Clin Res Cardiol. 2010;99(2):107-113. doi: 10.1007/s00392-009-0092-3; 10.1007/s00392-009-0092-3.
  16. Zhang L, Hiebert B, Zarychanski R, Arora RC, Cardiovascular Health Research in Manitoba (CHaRM) Investigator Group. Preoperative anemia does not increase the risks of early surgical revascularization after myocardial infarction. Ann Thorac Surg. 2013;95(2):542-547. doi: 10.1016/j.athoracsur.2012.07.011; 10.1016/j.athoracsur.2012.07.011.


  1. Goodnough LT, Maniatis A, Earnshaw P, et al. Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines. Br J Anaesth. 2011;106(1):13-22. doi: 10.1093/bja/aeq361; 10.1093/bja/aeq361.
  2. Johansson T, Pettersson LG, Lisander B. Tranexamic acid in total hip arthroplasty saves blood and money: A randomized, double-blind study in 100 patients. Acta Orthop. 2005;76(3):314-319.
  3. Oremus K, Sostaric S, Trkulja V, Haspl M. Influence of tranexamic acid on postoperative autologous blood retransfusion in primary total hip and knee arthroplasty: A randomized controlled trial. Transfusion. 2013. doi: 10.1111/trf.12224; 10.1111/trf.12224.
  4. Poultsides LA, Gonzalez Della Valle A, Memtsoudis SG, et al. Meta-analysis of cause of death following total joint replacement using different thromboprophylaxis regimens. J Bone Joint Surg Br. 2012;94(1):113-121. doi: 10.1302/0301-620X.94B1.27301; 10.1302/0301-620X.94B1.27301.
  5. Ralley FE, Berta D, Binns V, Howard J, Naudie DD. One intraoperative dose of tranexamic acid for patients having primary hip or knee arthroplasty. Clin Orthop Relat Res. 2010;468(7):1905-1911. doi: 10.1007/s11999-009-1217-8; 10.1007/s11999-009-1217-8.
  6. Zhang H, Chen J, Chen F, Que W. The effect of tranexamic acid on blood loss and use of blood products in total knee arthroplasty: A meta-analysis. Knee Surg Sports Traumatol Arthrosc. 2012;20(9):1742-1752. doi: 10.1007/s00167-011-1754-z; 10.1007/s00167-011-1754-z.